Rosanna Arquette as Nicole Varzi on "What About Brian"
Rosanna Arquette was born in New York City into a show business family, the first child of five in the third generation of the Arquette acting clan. Her grandfather, Cliff Arquette, played Charley Weaver on "The Jack Paar Show" and in the original "Hollywood Squares." Her father, character actor Lewis Arquette, was well known as J. D. Pickett on "The Waltons." And her siblings, Patricia Arquette, David Arquette, Alexis Arquette and Richmond Arquette, all followed her into the family tradition as accomplished working actors.
Rosanna began acting as a child while growing up in a bohemian atmosphere of gypsy-like travel and communes. Her mother, Mardi, was a poet, political activist and therapist who deeply influenced her daughter's compassionate world view.
Rosanna started working professionally as a teenager and has never stopped. Throughout her career Rosanna Arquette has worked with some of the most important and influential directors in Hollywood and independent film, including, Blake Edwards ("S.O.B."), John Sayles ("Baby It's You"), Lawrence Kasden ("Silverado"), Martin Scorsese ("After Hours," "New York Stories"), Luc Besson ("The Big Blue"), Quentin Tarantino ("Pulp Fiction"), David Cronenberg ("Crash"), Vincent Gallo ("Buffalo 66") and Alison Anders ("Sugar Town"). Rosanna Arquette has appeared in over 70 films.
Rosanna Arquette won the British Academy Award for Best Supporting Actress for her star-making performance opposite Madonna in Susan Seidleman's 1985 hit, "Desperately Seeking Susan." Rosanna Arquette was further nominated for an Emmy for her strong performance in the television adaptation of Norman Mailer's "The Executioner's Song," opposite Tommy Lee Jones. Rosanna Arquette starred in the acclaimed TV movie adaptations of "Song of the Morning Star "and "Johnny Belinda," and has guest starred in numerous television series, including "Grey's Anatomy," "Will and Grace," "The Practice," "Law and Order: Criminal Intent" and Showtime's provocative hit, "The L Word."
Rosanna Arquette is one of the few actresses who has the distinction of having a No. 1 hit song written about her—Toto's 1982 "Rosanna." Rosanna Arquette has hosted "Saturday Night Live" and has appeared on the cover of many magazines throughout the years.
Rosanna Arquette's vast experience in the film world has inspired her to explore and expand her talent as a filmmaker into the realm of directing and producing, and she has two highly acclaimed documentaries to her credit, 2002's "Searching for Debra Winger" and 2005's "All We Are Saying." Currently Rosanna Arquette is developing other projects, including her narrative film directorial debut, through her company, Flower Child Productions.
Rosanna Arquette's passion for her work is matched only by her passion for her daughter, Zoe Blue Sidel, a next generation actress, her family and her work as a breast cancer awareness advocate.