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CBS's "The Big Bang Theory" is a comedy from the Emmy Award nominated co-creator and executive producer of "Two and a Half Men" Chuck Lorre, about brainy best friends Leonard (Johnny Galecki, "Roseanne") and Sheldon (Jim Parsons "Judging Amy"), who can tell you anything you want to know about quantum physics, but when it comes to dealing with everyday life here on earth they're lost in the cosmos. Neither fully understands that scientific principles don't always apply in matters of the heart—until they meet their sexy new neighbor Penny (Kaley Cuoco, "8 Simple Rules ... ").

Penny is a friendly screenwriter/waitress from the midwest who also happens to be newly single. She quickly makes an impression on the other members of Leonard and Sheldon's geek squad: Howard Wolowitz (Simon Helberg, "Studio 60 on the Sunset Strip"), who portrays himself as the Casanova of Cal Tech, and fellow whiz kid Rajesh Koothrappali (Kunal Nayyar, "NCIS"), who is rendered speechless around anyone unprepared to converse about the Theory of Relativity or other scientific jargon.

While Leonard spends his days looking for love, Sheldon is quite content video-chatting with platonic partner Amy Farrah Fowler, or playing Star Trek 3D Chess with their ever-expanding universe of friends, including Wolowitz' new wife, the adorable microbiologist Bernadette.

The chemistry between this gaggle of geniuses and a delightful damsel is about to undergo a stimulating series of inter-personal experiments.

CBS's "The Big Bang Theory" is produced by Chuck Lorre Productions, Inc., in association with Warner Bros. Television. Multiple Emmy Award winner James Burrows ("Will & Grace") directed the pilot. Chuck Lorre and Bill Prady ("Gilmore Girls," "Dharma & Greg") are executive producers along with Lee Aronsohn.

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Network: CBS
Genre: Comedy
Runtime: 30 mins.
Premiere Date: September 24, 2007
Seasons: 10
Production Companies:
Chuck Lorre Productions
Warner Bros. Television

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Got The Big Bang Theory spoilers? What did you think of the last show?

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